Chargers vs. 49ers predictions: NFL Week 10 picks, offers, odds

Our NFL betting author brings you his finest Chargers at 49ers predictions and picks for his or her NFL Week 10 showdown, which is reside Sunday on NBC at 5:20 p.m. EST.

The Chargers (5-3) have a prime QB in Justin Herbert however have struggled with their dashing assault whereas additionally having points stopping opponents’ floor sport. Getting the ball into versatile RB Austin Ekeler’s palms has been a profitable technique however San Francisco will probably be geared as much as sluggish him down. The 49ers (4-4) are set to unveil the anticipated offensive duo of Deebo Samuel and Christian McCaffrey.

Chargers vs. 49ers picks


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Chargers vs. 49ers picks and evaluation

Loads of consideration has been dedicated to the Samuel-McCaffrey mixture and the way potent they'll make an offense with their hybrid types. Maybe simply as massive of an impression might be San Francisco’s dynamic protection and what they're able to in opposition to the Chargers.

49ers cowl -7

The Chargers’ protection has struggled in opposition to the run to the tune of 145.5 yards in opposition to per sport, which is fourth from the underside heading into Week 10. It's an ominous signal upfront of a sport the place their opponent will unleash a two-headed offensive onslaught.

McCaffrey’s quick-cutting working type with exact imaginative and prescient will give a contrasting look when in comparison with Samuel’s power-running type both with a hand off or after a catch. A continuing dashing barrage by the 49ers figures to have the Chargers reeling by the second half.

Most helpful of all to the 49ers is that they reduce the reliance on quarterback Jimmy Garoppolo, permitting him to give attention to being a mistake-free subject chief, which is a method that has served him effectively this season. He has 4 interceptions in 210 makes an attempt.

Chargers vs. 49ers prediction: 49ers to cowl -7 at -110 (Caesars Sportsbook)

Deebo Samuel of the San Francisco 49ers
Deebo Samuel of the San Francisco 49ers
Getty Pictures

Underneath 45.5 complete factors scored

Certain Samuel and McCaffrey have big-play potential. Samuel has proven that always, like his 57-yard TD reception from Garoppolo in Week 4 in opposition to the Rams. McCaffrey had a passing, dashing and receiving TD in Week 8 in opposition to the Rams.

However it's Samuel’s 5.8 yards per rush and McCaffrey’s 5.1 per try that stand out. It implies that on common, one rush from Samuel and one from McCaffrey equals a primary down. It additionally reveals a path for marching downfield and controlling time of possession.

And when the 49ers need to combine up the look, each gamers are capable of stand out as move catchers. The Chargers, in the meantime, struggled to attain factors in opposition to a below-average Falcons protection final week and now need to face among the best defenses within the sport.

Chargers vs. 49ers prediction: Underneath 45.5 complete factors scored at -110 (Caesars Sportsbook)

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49ers rating landing on first drive

In every of their final six video games, the 49ers have scored a landing in both their first or second drive of the sport. And that features Week 3 at Denver, once they discovered the top zone the second time they touched the ball then scored simply three factors the remainder of the best way.

The early scores present that San Francisco coach Kyle Shanahan can match his personnel with and a sport plan that takes benefit of the tendencies of opposing defenses. He even did it early with a protection as sturdy as what the Broncos placed on the sector.

The Chargers’ protection is just not in that class so anticipated Shanahan to be ready with a scripted first-drive package deal that highlights Samuel and McCaffrey, whereas additionally discovering the best spots for Garoppolo to ship when L.A. would possibly least count on it.

Chargers vs. 49ers prediction: 49ers rating landing on first drive at +245 (Caesars Sportsbook)

Chargers vs. 49ers odds

Odds courtesy of Caesars Sportsbook. Appropriate at time of publishing and topic to vary.

GroupUnfold MoneylineWhole Factors 45.5
Chargers(+7.0) -110+260Over -110
49ers (-7.0) +100-335Underneath -110 

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